The plot is about a middle-class girl, Geum Jan-di, becomes admitted to a rich, prestigious school known as Shinhwa. The school is filled with rich people who can afford to go there. She becomes admitted after saving a student from committing suicide. At the school, she meets people with various personalities. There are the mean girls, fake friends, and last but not least: The F4. The F4 consists of 4 people: Goo Jun Pyo, Yoon Ji Hoo, So Yi Jung, and Song Woo Bin. Goo Jun Pyo is the leader of the F4 and is also the heir of the Shinhwa group. At first, he insults and makes Geum Jan-di's life miserable after she humiliates him. The only person who seemed to have sympathy for her was Ji Hoo, who saved her numerous times. However, as the drama progressed, Goo Jun Pyo developed feelings for Geum Jan-di. It turned out to be a twisted love triangle between Geum Jan Di, Goo Jun Pyo and Yoon Ji Hoo.r of the F4 and is also the heir of the Shinhwa group.
At first, he insults and makes Geum Jan-di's life miserable after she humiliates him. The only person who seemed to have sympathy for her was Ji Hoo, who saved her numerous times. However, as the drama progressed, Goo Jun Pyo developed feelings for Geum Jan-di. It turned out to be a twisted love triangle between Geum Jan Di, Goo Jun Pyo and Yoon Ji Hoo.
* Koo Hye Sun:
Jan Di is from a poor family with a fierce and weed-like determination. She first liked Ji Hoo, who was the only one who showed any compassion while she was bullied. Eventually Jun Pyo begins to fall in love with her, and as he expresses his feelings towards her, she gradually begins to reciprocate those feelings. Jan Di later is determined to pursue the medical industry after realizing she can't swim because of her shoulder.
* Lee Min-ho:
Jun Pyo is the hot-headed leader of F4. Exasperated by Jan Di's act of defiance, he makes her a target of bullying. But as time passes, he begins to admire Jan di's determination and will and falls in love with her. He is the heir of Shinhwa Group, and after his father passes away, he inherits and begins to run the Shinhwa Group along with his mother.
* Kim Hyun-joong:
Ji Hoo is a calm and soft-spoken boy who likes to play the violin, piano and guitar and conduct an orchestra. Seo Hyeon was Ji Hoo's first love, after she helped him overcome trauma after the death of his parents when he was little. He attempts to fight for Seo Hyeon's love by following her to France. When he comes back, he has already realized that he had fallen for Jan Di. However, Jun Pyo has already announced his love of Jan Di. Ji Hoo decides not to betray his friend by trying to fight for Jan Di. He is a grandson of Korea's former president.
* Kim Bum: (소이정)
A playboy who often flirts with girls, Yi Jeong is himself a reputed potter. He is from a family of well-known artists, who own an art gallery exhibiting national treasures.
* Kim Joon: (송우빈)
From their origin in the underworld, Woo Bin's family now runs a prominent construction business. The family owns real estate throughout the country.
Geum (금) Family:
* Ahn Suk Hwan: Geum Il Bong (금일봉)
* Lim Ye Jin: Na Gong Ju (나공주)
* Park Ji Bin: Geum Kang San (금강산)
Gu (구) Family:
* Lee Hye Yeong: Gang Hui Su (강희수)
* Kim Hyun Joo: Gu Jun Hui (구준희)
* Jung Ho Bin: Jeong Seongrok (정성록)
* Han Chae Yeong: Min Seo Hyeon (민서현)
* Kim So Eun: Chu Ga Eul (추가을)
* Lee Shi Yeong: Oh Min Ji (오민지)
* Lee Min Jeong: Ha Jae Kyeong (하재경)
Mean Trio (Jin Sun Mi):
* Gook Ji Yeon: 최진희 (known as Ginger)
* Jang Ja Yeon: 박선자 (known as Sunny)
* Min Yeong Won: 이미숙 (known as Miranda)
* Jung Ui Chul: Lee Min Ha / Min Jae Ha
* Kim Min Ji: Jang Yoo Mi
Differences between the other versions
* In the Taiwan Meteor Garden version, Jan Di's character was an only child. In the Japanese and Korean version, she has a younger brother.
* In the Taiwan Meteor Garden version, the heroine attends college. In the Japanese version, the characters are in high school in season 1, but F4 (minus Domyoji) attend Eitoku University in season 2. In the Korean Boys Over Flower version, the characters are also in high school, but the F4 move on to Shinhwa University from episode 13 onwards. Shinhwa High School and Shinhwa University are located within the same campus.
* In Taiwan Meteor Garden and Japanese Hanayori Dango version, Jan Di’s character was already studying at the school for rich people. In Korean Boys Over Flower (or Boys Before Flower) version, Jan Di was admitted after saving a boy for jumping off the roof of Shinhwa High School on a swimming scholarship.
* In both Taiwan Meteor Garden and Japanese Hanayori Dango version, the relationship between the two characters: Sojiroh and Yuki ( also known as Yi Jung and Ga Eul in the Korean version) is only hinted. But in the Korean Boys Over Flower (or Boys Before Flower) version, the relationship between these two is gradually developed throughout the series, being a significant plotline instead of a subplot.
* Akira, the fourth member of the group, seems to be the youngest in Japanese version, and is unknown in Taiwanese version. In Korean Boys Over Flower (or Boys Before Flower) version, Song Woo Bin seems to be the oldest of the four.
* The Korean Boys Over Flower (or Boys Before Flower) version also explores into Ji Hoo and Jan Di's relationship more, much more strongly than the Taiwanese and Japanese version.